



If you’ve heard about ChondroFiller , you might ask: if it isn’t stitched into the cartilage, how does it actually stay in place? ChondroFiller is an innovative implant made from type I collagen. It starts off as a liquid and then transforms into a gel, neatly filling the damaged area. Because it’s applied in a single, straightforward step, ChondroFiller offers a minimally invasive alternative to more complex cartilage repair surgeries. Recent studies describe ChondroFiller Liquid® as a resorbable filler designed to create a protective layer over the cartilage defect while encouraging the growth of new cartilage cells (Corain et al., 2023).
ChondroFiller ’s effectiveness comes from its clever two-part application: a collagen liquid is mixed with a special solution that triggers gel formation exactly where it’s needed. As it sets, the material molds to the unique shape of each patient’s cartilage injury . The result is a custom-fit “joint-shaped” gel that snugly fills the defect, matching the natural contours of the joint and helping to anchor it firmly in place. Clinical studies have shown improvements in pain and grip strength after its use.
What truly sets ChondroFiller apart is its natural ability to adhere to the surrounding cartilage. As the collagen gel forms, it creates a fibrous network that connects closely with nearby tissue—almost like a natural glue. This provides a stable bond, allowing the implant to stay in place even as the joint moves, bends, or bears weight during daily activities. In some patients, MRI scans have demonstrated improvements in joint profile and reductions in swelling following treatment (Corain et al., 2023).
Research in animal models, such as mini-pigs, has shown that ChondroFiller helps repair cartilage defects by encouraging the migration of new cells and the formation of type II collagen, which is vital for healthy cartilage . In human studies, patients have reported improved grip strength and a potential improvement in hand and arm function scores after treatment (Corain et al., 2023). Safety outcomes are positive, with improvements in both pain and function. Ongoing MRI research is helping doctors better understand how these positive clinical results relate to changes seen on scans.
At London Cartilage Clinic, patients are cared for by Professor Paul Lee, a highly regarded specialist in orthopaedics and rehabilitation. The clinic provides comprehensive support, combining advanced imaging with a team approach to ensure the best possible outcomes for each patient’s recovery. While neither Professor Lee nor the clinic invented ChondroFiller , their expertise helps patients make informed choices about their care.
ChondroFiller ’s ability to remain securely in place, even without stitches, is due to its unique gel-forming process and natural adhesive properties—both backed by encouraging clinical and laboratory research. This custom-fit gel scaffold maintains stability even during joint movement , offering a reliable and minimally invasive solution for cartilage repair . For personal medical guidance, always consult a qualified healthcare professional.
Corain, M., Zanotti, F., Giardini, M., Gasperotti, L., Invernizzi, E., Biasi, V., & Lavagnolo, U. (2023). The Use of an Acellular Collagen Matrix ChondroFiller® Liquid for Trapeziometacarpal Osteoarthritis. , , . https://doi.org/10.1177/19476035251354926
Perez-Carro, L., Rosi Mendoza Alejo, P., Gutierrez Castanedo, G., Menendez Solana, G., Fernandez Divar, J. A., Galindo Rubin, P., & Alfonso Fernandez, A. (2021). Hip Chondral Defects: Arthroscopic Treatment With the Needle and Curette Technique and ChondroFiller. Arthroscopy Techniques, , . https://doi.org/10.1016/j.eats.2021.03.011
De Lucas Villarrubi, J. C., Méndez Alonso, M. Á., Sanz Pérez, M. I., Trell Lesmes, F., & Panadero Tapia, A. (2021). Acellular Matrix-Induced Chondrogenesis Technique Improves the Results of Chondral Lesions Associated With Femoroacetabular Impingement. Arthroscopy, , . https://doi.org/10.1016/j.arthro.2021.08.022
ChondroFiller becomes a gel once applied, naturally adhering to the joint’s unique shape. This custom-fit process forms a stable, joint-shaped scaffold that remains in place securely without the need for stitches, even during movement or weight-bearing activities.
London Cartilage Clinic combines advanced imaging with a multi-disciplinary team, ensuring expert assessment and aftercare. Professor Paul Lee’s experience and collaborative approach enable patients to benefit from state-of-the-art techniques and a personalised, supportive care pathway during their cartilage repair journey.
Yes, ChondroFiller is applied in a single, straightforward step, making it far less invasive than complex cartilage repair surgeries. This means reduced disruption for patients, and potentially quicker recovery, all under the dedicated care of Professor Lee and the London Cartilage Clinic team.
Clinical studies report improvements in pain, grip strength, and overall joint function following ChondroFiller application. MRI scans and patient feedback suggest better joint profile and reduced swelling post-procedure. The clinic’s use of advanced imaging further supports careful monitoring throughout recovery.
Professor Paul Lee is a distinguished orthopaedic and rehabilitation specialist with years of experience in cartilage conditions. His guidance at London Cartilage Clinic ensures each patient receives tailored, evidence-based care—helping them understand all their options and supporting the best possible recovery.
All our treatments are selected to help patients achieve the best possible outcomes and return to the quality of life they deserve. Get in touch if you have any questions.
At London Cartilage Clinic, we are constantly staying up-to-date on the latest treatment options for knee injuries and ongoing knee health issues. As a result, our patients have access to the best equipment, techniques, and expertise in the field, whether it’s for cartilage repair, regeneration, or replacement.
For the best in patient care and cartilage knowledge, contact London Cartilage Clinic today.
At London Cartilage Clinic, our team has spent years gaining an in-depth understanding of human biology and the skills necessary to provide a wide range of cartilage treatments. It’s our mission to administer comprehensive care through innovative solutions targeted at key areas, including cartilage injuries. During an initial consultation, one of our medical professionals will establish which path forward is best for you.
Contact us if you have any questions about the various treatment methods on offer.
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